Metastatic Breast Cancer LM Webinar

by | Oct 13, 2025 | LM

Did you know that as many as 5% to 20% of people with advanced breast cancer may eventually develop leptomeningeal metastases (LM) — also known as leptomeningeal disease (LMD)?

LM occurs when cancer cells spread to the membranes (meninges) that surround the brain and spinal cord. It’s a rare and serious complication, most often seen in patients with breast, lung, melanoma, or gastrointestinal cancers. Because the symptoms can be subtle or resemble other conditions, early recognition is critical.

Common signs of LM may include:

  • Persistent headaches or nausea

  • Vision or hearing changes

  • Balance or coordination issues

  • Confusion or memory problems

  • Weakness or numbness in the arms or legs

Learn more about LM symptoms and diagnosis from the National Cancer Institute.

Join the Leptomeningeal Cancer Foundation for an Educational Webinar

This Friday, October 24th, the Leptomeningeal Cancer Foundation will host a live virtual discussion featuring two leading experts in breast cancer and leptomeningeal metastases.

What to Expect:

  • Latest research on leptomeningeal metastases in breast cancer

  • Insights from clinicians on diagnosis and treatment

  • Information about current clinical trials

  • Open Q&A with medical experts

Date: Friday, October 24
Time: 9:00 AM ET
Register here: https://bit.ly/4nvGaex

This free event is open to patients, caregivers, and clinicians who want to better understand LM and the future of treatment research.

The ReSPECT-LM Clinical Trial: A New Approach to Treating LM

At Plus Therapeutics, we’re advancing the ReSPECT-LM clinical trial, evaluating REYOBIQ™ (rhenium-186 nanoliposomes) — a targeted radiotherapeutic designed to deliver radiation precisely to cancer cells within the cerebrospinal fluid (CSF).

Unlike systemic chemotherapy, this investigational treatment is delivered directly to the central nervous system through a small catheter placed under the scalp, aiming to maximize tumor exposure and minimize toxicity to the rest of the body.

Learn more about the study, participating locations, and eligibility:
www.respect-trials.com

Patients or caregivers can also visit the ReSPECT-LM eligibility page to see if participation may be an option.

Knowledge and Connection Drive Progress

Events like this webinar play a vital role in improving patient outcomes. By raising awareness and advancing research, we move closer to the goal of providing safe, effective, and targeted therapies for people living with LM.